Donkey Secondary Antibodies
Biotium CDX2 / Caudal Type Homeobox 2 (GI Epithelial Marker)(CDX2/2214), CF647 conjugate, 0.1mg/mL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19, 000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of bl
Biotium Cytokeratin, Basic (Type II or HMW)(KRTH/2147R), CF647 conjugate, 0.1mg/mL
This antibody recognizes CK1, CK5, CK10 and CK14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This MAb shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands; there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this antibody. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. This antibody has also been useful in separating benign from malignant intraductal breast proliferations. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, b
Jackson Immuno Research Labs DONKEY ANTI MOUSE IGG
Fluorescein (FITC)-AffiniPure F(ab')2 Fragment Donkey Anti-Mouse IgG (H+L) (min X Bov,Ck,Gt,GP,Sy Hms,Hrs,Hu,Rb,Shp Sr Prot)
Jackson Immuno Research Labs Biotin-SP (long spacer) AffiniPure F(ab')₂ Fragment Donkey Anti-Mouse IgG (H+L), .3ml
Biotin-SP-AffiniPure F(ab')2 Fragment Donkey Anti-Mouse IgG (H+L) (min X Bov,Ck,Gt,GP,Sy Hms,Hrs,Hu,Rb,Rat,Shp Sr Prot)
Jackson Immuno Research Labs ANTI-HUMAN IGM
AffiniPure F(ab')2 Fragment Donkey Anti-Human IgM, Fc5u Fragment Specific (min X Bov,Hrs Sr Prot)
Jackson Immuno Research Labs Fluorescein (FITC)-AffiniPure Fab Fragment Donkey Anti-Goat IgG (H+L)
Fluorescein (FITC)-AffiniPure Fab Fragment Donkey Anti-Goat IgG (H+L)
Jackson Immuno Research Labs 18nm Colloidal Gold-AffiniPure Donkey Anti-Goat IgG (H+L) (min X Ck GP Sy Hms Hrs Hu Ms Rb Rat Sr Prot) (EM Grade)
18nm Colloidal Gold-AffiniPure Donkey Anti-Goat IgG (H+L) (min X Ck GP Sy Hms Hrs Hu Ms Rb Rat Sr Prot) (EM Grade)
Biotium Cytokeratin, Basic (Type II or HMW)(KRTH/2147R), CF647 conjugate, 0.1mg/mL
This antibody recognizes CK1, CK5, CK10 and CK14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This MAb shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands; there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this antibody. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. This antibody has also been useful in separating benign from malignant intraductal breast proliferations. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, b
Biotium NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker)(NX2/2198R), CF647 conjugate, 0.1mg/mL
Expression of NKX2. 2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2. 2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium Squamous Cell Carcinoma Antigen 1(CPTC-SERPINB3-2), CF647 conjugate, 0.1mg/mL
Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine proteases, such as neutrophil elastase. Serpins are family of serine protease inhibitors, contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. Serine proteases bind to this substrate mimic in a 1:1 stoichiometric fashion and become catalytically inactive. Aberrant expression of serpin family members can contribute to a number of conditions, including emphysema (-1 antitrypsin deficiency), fatal bleeding (elastase to Thrombin specificity) and thrombosis (antithrombin deficiency), and are indicators of cancer stage phenotypes (circulating levels of squamous cell carcinoma antigen, known as SCCA1, increase in advancing stages of some cervical, lung, esophageal and head and neck cancers). SCCA1 expression has been demonstrated
Jackson Immuno Research Labs AMCA-AffiniPure Donkey Anti-Goat IgG (H+L) (min X Ck GP Sy Hms Hrs Hu Ms Rb Rat Sr Prot)
AMCA-AffiniPure Donkey Anti-Goat IgG (H+L) (min X Ck GP Sy Hms Hrs Hu Ms Rb Rat Sr Prot)
Jackson Immuno Research Labs Biotin-SP-AffiniPure Fab Fragment Donkey Anti-Goat IgG (H+L)
Biotin-SP-AffiniPure Fab Fragment Donkey Anti-Goat IgG (H+L)
Jackson Immuno Research Labs Biotin-SP-AffiniPure F(ab')2 Fragment Donkey Anti-Chicken IgY (IgG) (H+L) (min X Bov Gt GP Sy Hms Hrs Hu Ms Rb Rat Shp Sr Prot)
Biotin-SP-AffiniPure F(ab')2 Fragment Donkey Anti-Chicken IgY (IgG) (H+L) (min X Bov Gt GP Sy Hms Hrs Hu Ms Rb Rat Shp Sr Prot)
Jackson Immuno Research Labs Rhodamine Red-X-AffiniPure Fab Fragment Donkey Anti-Goat IgG (H+L)
Rhodamine Red-X-AffiniPure Fab Fragment Donkey Anti-Goat IgG (H+L)
Jackson Immuno Research Labs DyLight 405-AffiniPure F(ab')2 Fragment Donkey Anti-Goat IgG (H+L) (min X Ck GP Sy Hms Hrs Hu Ms Rb Rat Sr Prot)
DyLight 405-AffiniPure F(ab')2 Fragment Donkey Anti-Goat IgG (H+L) (min X Ck GP Sy Hms Hrs Hu Ms Rb Rat Sr Prot)